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Titel:

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
Autor(en):
Mattila, Markus; Erlund, Iris; Lee, Hye-Seung; Niinistö, Sari; Uusitalo, Ulla; Andrén Aronsson, Carin; Hummel, Sandra; Parikh, Hemang; Rich, Stephen S; Hagopian, William; Toppari, Jorma; Lernmark, Åke; Ziegler, Anette G; Rewers, Marian; Krischer, Jeffrey P; Norris, Jill M; Virtanen, Suvi M
Abstract:
AIMS/HYPOTHESIS: We studied the association of plasma ascorbic acid with the risk of developing islet autoimmunity and type 1 diabetes and examined whether SNPs in vitamin C transport genes modify these associations. Furthermore, we aimed to determine whether the SNPs themselves are associated with the risk of islet autoimmunity or type 1 diabetes. METHODS: We used a risk set sampled nested case-control design within an ongoing international multicentre observational study: The Environmental Det...     »
Zeitschriftentitel:
Diabetologia
Jahr:
2020
Band / Volume:
63
Heft / Issue:
2
Seitenangaben Beitrag:
278-286
Volltext / DOI:
doi:10.1007/s00125-019-05028-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31728565
Print-ISSN:
0012-186X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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