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Title:

HCoV- and SARS-CoV-2 Cross-Reactive T Cells in CVID Patients.

Document type:
Article; Journal Article
Author(s):
Steiner, Sophie; Sotzny, Franziska; Bauer, Sandra; Na, Il-Kang; Schmueck-Henneresse, Michael; Corman, Victor M; Schwarz, Tatjana; Drosten, Christian; Wendering, Désirée J; Behrends, Uta; Volk, Hans-Dieter; Scheibenbogen, Carmen; Hanitsch, Leif G
Abstract:
The inability of patients with CVID to mount specific antibody responses to pathogens has raised concerns on the risk and severity of SARS-CoV-2 infection, but there might be a role for protective T cells in these patients. SARS-CoV-2 reactive T cells have been reported for SARS-CoV-2 unexposed healthy individuals. Until now, there is no data on T cell immunity to SARS-CoV-2 infection in CVID. This study aimed to evaluate reactive T cells to human endemic corona viruses (HCoV) and to study pre-e...     »
Journal title abbreviation:
Front Immunol
Year:
2020
Journal volume:
11
Fulltext / DOI:
doi:10.3389/fimmu.2020.607918
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33424856
Print-ISSN:
1664-3224
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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