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Title:

Assessing haemorrhage-critical values of cerebral blood flow by modelling biomechanical stresses on capillaries in the immature brain.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Sidorenko, Irina; Turova, Varvara; Botkin, Nikolai; Kovtanyuk, Andrey; Eckardt, Laura; Alves-Pinto, Ana; Felderhoff-Müser, Ursula; Rieger-Fackeldey, Esther; Lampe, Renée
Abstract:
The development of intraventricular haemorrhages (IVH) in preterm newborns is triggered by a disruption of the vessels responsible for cerebral microcirculation. Analysis of the stresses exerted on vessel walls enables the identification of the critical values of cerebral blood flow (CBF) associated with the development of IVH in preterm infants. The purpose of the present study is the estimation of these critical CBF values using the biomechanical stresses obtained by the finite element modelli...     »
Journal title abbreviation:
Sci Rep
Year:
2020
Journal volume:
10
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-020-71087-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32848187
Print-ISSN:
2045-2322
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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