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Titel:

Identification and Cloning of a New Western Epstein-Barr Virus Strain That Efficiently Replicates in Primary B Cells.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Delecluse, Susanne; Poirey, Remy; Zeier, Martin; Schnitzler, Paul; Behrends, Uta; Tsai, Ming-Han; Delecluse, Henri-Jacques
Abstract:
The Epstein-Barr virus (EBV) causes human cancers, and epidemiological studies have shown that lytic replication is a risk factor for some of these tumors. This fits with the observation that EBV M81, which was isolated from a Chinese patient with nasopharyngeal carcinoma, induces potent virus production and increases the risk of genetic instability in infected B cells. To find out whether this property extends to viruses found in other parts of the world, we investigated 22 viruses isolated fro...     »
Zeitschriftentitel:
J Virol
Jahr:
2020
Band / Volume:
94
Heft / Issue:
10
Volltext / DOI:
doi:10.1128/JVI.01918-19
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32102884
Print-ISSN:
0022-538X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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