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Title:

Imaging of cardiac fibroblast activation in a patient after acute myocardial infarction using 68Ga-FAPI-04

Document type:
Zeitschriftenaufsatz
Author(s):
Notohamiprodjo, Susan; Nekolla, Stephan G.; Robu, Stephanie; Villagran Asiares, Alberto; Kupatt, Christian; Ibrahim, Tareq; Laugwitz, Karl-Ludwig; Makowski, Marcus R.; Schwaiger, Markus; Weber, Wolfgang A.; Varasteh, Zohreh
Abstract:
Our previous study has demonstrated the feasibility of noninvasive imaging of fibroblast activation protein (FAP)-expression after myocardial infarction (MI) in MI-territory in a rat model with 68Ga-FAPI-04-PET. In the current extended clinical case, we sought to delineate cardiac uptake of 68Ga-FAPI-04 in a patient after MI with clinical indication for the evidence of fibroblast activation. Carcinoma patients without cardiac disease underwent 68Ga-FAPI-04-PET/CT as control. The patient with one...     »
FP7 Project ID:
764458
Horizon 2020:
This work is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No 764458.
Journal title:
Journal of Nuclear Cardiology
Year:
2021
Fulltext / DOI:
doi:10.1007/s12350-021-02603-z
Publisher:
Springer Science and Business Media LLC
E-ISSN:
1071-35811532-6551
Date of publication:
15.04.2021
Copyright statement:
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