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Title:

PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma.

Document type:
Journal Article
Author(s):
Vag, Tibor; Steiger, Katja; Rossmann, Andreas; Keller, Ulrich; Noske, Aurelia; Herhaus, Peter; Ettl, Johannes; Niemeyer, Markus; Wester, Hans-Jürgen; Schwaiger, Markus
Abstract:
BACKGROUND: CXCR4 is a chemokine receptor frequently overexpressed in invasive breast cancer that has been shown to play a major role in signaling pathways involved in metastasis. The aim of this retrospective analysis was to assess the diagnostic performance of CXCR4-directed PET imaging in patients with breast cancer using the recently introduced CXCR4-targeted PET probe 68Ga-Pentixafor. RESULTS: Thirteen patients with first diagnosis of breast cancer, four patients with recurrent disease afte...     »
Journal title abbreviation:
EJNMMI Res
Year:
2018
Journal volume:
8
Journal issue:
1
Pages contribution:
90
Language:
eng
Fulltext / DOI:
doi:10.1186/s13550-018-0442-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30191351
Print-ISSN:
2191-219X
TUM Institution:
Frauenklinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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