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Title:

PET imaging with [(18)F]3'-deoxy-3'-fluorothymidine for prediction of response to neoadjuvant treatment in patients with rectal cancer.

Document type:
Journal Article; Article
Author(s):
Wieder, HA; Geinitz, H; Rosenberg, R; Lordick, F; Becker, K; Stahl, A; Rummeny, E; Siewert, JR; Schwaiger, M; Stollfuss, J
Abstract:
PURPOSE: Positron emission tomography (PET) using( 18)F-labelled 3'-deoxy-3'-fluorothymidine (FLT) was assessed for therapy monitoring in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy. METHODS: Ten patients with locally advanced rectal cancer were included and underwent long-course preoperative chemoradiotherapy (total dose 45 Gy, 1.8 Gy/day, concomitant 250 mg/m(2) 5-fluorouracil) followed by surgery. FLT-PET was performed prior to chemoradiotherapy, 2 weeks after initiat...     »
Journal title abbreviation:
Eur J Nucl Med Mol Imaging
Year:
2007
Journal volume:
34
Journal issue:
6
Pages contribution:
878-83
Language:
eng
Fulltext / DOI:
doi:10.1007/s00259-006-0292-2
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17195074
Print-ISSN:
1619-7070
TUM Institution:
Chirurgische Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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