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Titel:

Visualizing cellularity and angiogenesis in newly-diagnosed glioblastoma with diffusion and perfusion MRI and FET-PET imaging.

Dokumenttyp:
Journal Article
Autor(en):
Liesche-Starnecker, Friederike; Prokop, Georg; Yakushev, Igor; Preibisch, Christine; Delbridge, Claire; Meyer, Hanno S; Aftahy, Kaywan; Barz, Melanie; Meyer, Bernhard; Zimmer, Claus; Schlegel, Jürgen; Wiestler, Benedikt; Gempt, Jens
Abstract:
PURPOSE: Combining imaging modalities has become an essential tool for assessment of tumor biology in glioblastoma (GBM) patients. Aim of this study is to understand how tumor cellularity and neovascularization are reflected in O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography ([18F] FET PET) and magnetic resonance imaging (MRI) parameters, including cerebral blood volume (CBV), fractional anisotropy (FA) and mean diffusivity (MD). METHODS: In this prospective cohort, 162 targeted b...     »
Zeitschriftentitel:
EJNMMI Res
Jahr:
2021
Band / Volume:
11
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s13550-021-00817-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34398358
Print-ISSN:
2191-219X
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin; Neurochirurgische Klinik und Poliklinik
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