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Titel:

PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Vag, Tibor; Steiger, Katja; Rossmann, Andreas; Keller, Ulrich; Noske, Aurelia; Herhaus, Peter; Ettl, Johannes; Niemeyer, Markus; Wester, Hans-Jürgen; Schwaiger, Markus
Abstract:
BACKGROUND: CXCR4 is a chemokine receptor frequently overexpressed in invasive breast cancer that has been shown to play a major role in signaling pathways involved in metastasis. The aim of this retrospective analysis was to assess the diagnostic performance of CXCR4-directed PET imaging in patients with breast cancer using the recently introduced CXCR4-targeted PET probe 68Ga-Pentixafor. RESULTS: Thirteen patients with first diagnosis of breast cancer, four patients with recurrent disease afte...     »
Zeitschriftentitel:
EJNMMI Res
Jahr:
2018
Band / Volume:
8
Heft / Issue:
1
Seitenangaben Beitrag:
90
Sprache:
eng
Volltext / DOI:
doi:10.1186/s13550-018-0442-0
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30191351
Print-ISSN:
2191-219X
TUM Einrichtung:
Frauenklinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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