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Titel:

T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease.

Dokumenttyp:
Observational Study; Journal Article
Autor(en):
Rahmani, Farzaneh; Brier, Matthew R; Gordon, Brian A; McKay, Nicole; Flores, Shaney; Keefe, Sarah; Hornbeck, Russ; Ances, Beau; Joseph-Mathurin, Nelly; Xiong, Chengjie; Wang, Guoqiao; Raji, Cyrus A; Libre-Guerra, Jorge J; Perrin, Richard J; McDade, Eric; Daniels, Alisha; Karch, Celeste; Day, Gregory S; Brickman, Adam M; Fulham, Michael; Jack, Clifford R; la La Fougère, Christian; Reischl, Gerald; Schofield, Peter R; Oh, Hwamee; Levin, Johannes; Vöglein, Jonathan; Cash, David M; Yakushev, Igor; I...     »
Abstract:
Carriers of mutations responsible for dominantly inherited Alzheimer disease provide a unique opportunity to study potential imaging biomarkers. Biomarkers based on routinely acquired clinical MR images, could supplement the extant invasive or logistically challenging) biomarker studies. We used 1104 longitudinal MR, 324 amyloid beta, and 87 tau positron emission tomography imaging sessions from 525 participants enrolled in the Dominantly Inherited Alzheimer Network Observational Study to extrac...     »
Zeitschriftentitel:
Hum Brain Mapp
Jahr:
2023
Band / Volume:
44
Heft / Issue:
18
Seitenangaben Beitrag:
6375-6387
Volltext / DOI:
doi:10.1002/hbm.26514
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37867465
Print-ISSN:
1065-9471
TUM Einrichtung:
170; 617; Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)
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