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Title:

Human platelet lysate successfully promotes proliferation and subsequent chondrogenic differentiation of adipose-derived stem cells: a comparison with articular chondrocytes.

Document type:
Journal Article
Author(s):
Hildner, F; Eder, M J; Hofer, K; Aberl, J; Redl, H; van Griensven, M; Gabriel, C; Peterbauer-Scherb, A
Abstract:
Fetal calf serum (FCS) bears a potential risk for carrying diseases and eliciting immune reactions. Nevertheless, it still represents the gold standard as medium supplement in cell culture. In the present study, human platelet lysate (PL) was tested as an alternative to FCS for the expansion and subsequent chondrogenic differentiation of human adipose-derived stem cells (ASCs). ASCs were expanded with 10% FCS (group F) or 5% PL (group P). Subsequently, three-dimensional (3D) micromass pellets we...     »
Journal title abbreviation:
J Tissue Eng Regen Med
Year:
2015
Journal volume:
9
Journal issue:
7
Pages contribution:
808-18
Fulltext / DOI:
doi:10.1002/term.1649
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23303715
Print-ISSN:
1932-6254
TUM Institution:
Klinik und Poliklinik für Unfallchirurgie
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