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Titel:

Linking Complement C3 and B Cells in Nasal Polyposis.

Dokumenttyp:
Article; Journal Article
Autor(en):
Werner, Ulrike; Künstner, Axel; Drenckhan, Maren; Pries, Ralph; Bruchhage, Karl-Ludwig; Busch, Hauke S; Bachert, Claus; Wollenberg, Barbara
Abstract:
Nasal polyposis often is characterized by a persistent inflammation of the sinonasal mucosa, disease recurrence after medical or surgical intervention, and asthma comorbidity. Dysregulated complement activation may contribute to immunologic alterations and disease. To date, there is only scattered knowledge on the source and regulation of the central complement factors in the pathogenesis of nasal polyps. Here, we aim to study complement signatures, especially the C3-C3aR axis, and focus on cell...     »
Zeitschriftentitel:
J Immunol Res
Jahr:
2020
Band / Volume:
2020
Volltext / DOI:
doi:10.1155/2020/4832189
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32724828
Print-ISSN:
2314-8861
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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