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Titel:

Vascularization of engineered cartilage constructs in a mouse model.

Dokumenttyp:
Journal Article
Autor(en):
Burghartz, Marc; Gehrke, Thomas; Storck, Katharina; Staudenmaier, Rainer; Mandlik, Veronika; Schurr, Christian; Hoang, Nguyen; Hagen, Rudolf; Kleinsasser, Norbert
Abstract:
Tissue engineering of cartilage tissue offers a promising method for reconstructing ear, nose, larynx and trachea defects. However, a lack of sufficient nutrient supply to cartilage constructs limits this procedure. Only a few animal models exist to vascularize the seeded scaffolds. In this study, polycaprolactone (PCL)-based polyurethane scaffolds are seeded with 1 × 10(6) human cartilage cells and implanted in the right hind leg of a nude mouse using an arteriovenous flow-through vessel loop f...     »
Zeitschriftentitel:
Cell Tissue Res
Jahr:
2015
Band / Volume:
359
Heft / Issue:
2
Seitenangaben Beitrag:
479-87
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00441-014-2026-2
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25381568
Print-ISSN:
0302-766X
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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