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Title:

The role of bradykinin receptor type 2 in spontaneous extravasation in mice skin: implications for non-allergic angio-oedema.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bisha, Marion; Dao, Vu Thao-Vi; Gholamreza-Fahimi, Ehsan; Vogt, Michael; van Zandvoort, Marc; Weber, Sarah; Bas, Murat; Khosravani, Farbod; Kojda, Georg; Suvorava, Tatsiana
Abstract:
Non-allergic angio-oedema is a life-threatening disease mediated by activation of bradykinin type 2 receptors (B receptors). The aim of this study was to investigate whether activation of B receptors by endogenous bradykinin contributes to physiological extravasation. This may shed new light on the assumption that treatment with an angiotensin converting enzyme inhibitor (ACEi) results in an alteration in the vascular barrier function predisposing to non-allergic angio-oedema.We generated a new...     »
Journal title abbreviation:
Br J Pharmacol
Year:
2018
Journal volume:
175
Journal issue:
10
Pages contribution:
1607-1620
Language:
eng
Fulltext / DOI:
doi:10.1111/bph.14166
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29465763
Print-ISSN:
0007-1188
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik
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