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Titel:

Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Grabowska, Joanna; Léopold, Valentine; Olesek, Katarzyna; Nijen Twilhaar, Maarten K; Affandi, Alsya J; Brouwer, Mieke C; Jongerius, Ilse; Verschoor, Admar; van Kooten, Cees; van Kooyk, Yvette; Storm, Gert; van 't Veer, Cornelis; den Haan, Joke M M
Abstract:
Historically platelets are mostly known for their crucial contribution to hemostasis, but there is growing understanding of their role in inflammation and immunity. The immunomodulatory role of platelets entails interaction with pathogens, but also with immune cells including macrophages and dendritic cells (DCs), to activate adaptive immune responses. In our previous work, we have demonstrated that splenic CD169+ macrophages scavenge liposomes and collaborate with conventional type 1 DCs (cDC1)...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2023
Band / Volume:
14
Volltext / DOI:
doi:10.3389/fimmu.2023.1290272
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/38054006
Print-ISSN:
1664-3224
TUM Einrichtung:
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (Prof. Wollenberg)
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