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Titel:

The role of bradykinin receptor type 2 in spontaneous extravasation in mice skin: implications for non-allergic angio-oedema.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Bisha, Marion; Dao, Vu Thao-Vi; Gholamreza-Fahimi, Ehsan; Vogt, Michael; van Zandvoort, Marc; Weber, Sarah; Bas, Murat; Khosravani, Farbod; Kojda, Georg; Suvorava, Tatsiana
Abstract:
Non-allergic angio-oedema is a life-threatening disease mediated by activation of bradykinin type 2 receptors (B receptors). The aim of this study was to investigate whether activation of B receptors by endogenous bradykinin contributes to physiological extravasation. This may shed new light on the assumption that treatment with an angiotensin converting enzyme inhibitor (ACEi) results in an alteration in the vascular barrier function predisposing to non-allergic angio-oedema.We generated a new...     »
Zeitschriftentitel:
Br J Pharmacol
Jahr:
2018
Band / Volume:
175
Heft / Issue:
10
Seitenangaben Beitrag:
1607-1620
Sprache:
eng
Volltext / DOI:
doi:10.1111/bph.14166
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29465763
Print-ISSN:
0007-1188
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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