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Titel:

Toward the development of rational therapies in multiple sclerosis: what is on the horizon?

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Hemmer, B; Hartung, HP
Abstract:
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support an autoimmune pathogenesis on the background of a complex interaction between multiple genes and environmental factors. Accordingly, targeting the immune system has been a rational approach for the treatment of MS. The development of disease-modifying immunomodulatory drugs with partial efficacy, coupled with advances in understanding the pathophysiology and pathology of MS, has provided momentum to explore...     »
Zeitschriftentitel:
Ann Neurol
Jahr:
2007
Band / Volume:
62
Heft / Issue:
4
Seitenangaben Beitrag:
314-26
Sprache:
eng
Volltext / DOI:
doi:10.1002/ana.21289
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17969020
Print-ISSN:
0364-5134
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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