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Title:

The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer.

Document type:
Journal Article
Author(s):
Rühlmann, Felix; Nietert, Manuel; Sprenger, Thilo; Wolff, Hendrik A; Homayounfar, Kia; Middel, Peter; Bohnenberger, Hanibal; Beissbarth, Tim; Ghadimi, B Michael; Liersch, Torsten; Conradi, Lena-Christin
Abstract:
The cellular sarcoma gene (SRC) is a proto-oncogene encoding for a tyrosine kinase. SRC expression was determined in locally advanced rectal adenocarcinoma tissue from pretreatment biopsies and resection specimens. The expression level was correlated with clinicopathological parameters to evaluate the predictive and prognostic capacity. For this monocentric analysis 186 patients with locally advanced rectal cancer (median: 63.7 years; 130 men (69.9%), 56 women (30.1%)) were included. Patients w...     »
Journal title abbreviation:
J Cancer
Year:
2017
Journal volume:
8
Journal issue:
7
Pages contribution:
1229-1237
Language:
eng
Fulltext / DOI:
doi:10.7150/jca.16980
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28607598
Print-ISSN:
1837-9664
TUM Institution:
Neurologische Klinik und Poliklinik
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