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Document type:
Journal Article
Author(s):
Moon, Jisook; Schwarz, Sigrid C; Lee, Hyun-Seob; Kang, Jun Mo; Lee, Young-Eun; Kim, Bona; Sung, Mi-Young; Höglinger, Gunter; Wegner, Florian; Kim, Jin Su; Chung, Hyung-Min; Chang, Sung Woon; Cha, Kwang Yul; Kim, Kwang-Soo; Schwarz, Johannes
Title:
Preclinical Analysis of Fetal Human Mesencephalic Neural Progenitor Cell Lines: Characterization and Safety In Vitro and In Vivo.
Abstract:
We have developed a good manufacturing practice for long-term cultivation of fetal human midbrain-derived neural progenitor cells. The generation of human dopaminergic neurons may serve as a tool of either restorative cell therapies or cellular models, particularly as a reference for phenotyping region-specific human neural stem cell lines such as human embryonic stem cells and human inducible pluripotent stem cells. We cultivated 3 different midbrain neural progenitor lines at 10, 12, and 14 we...     »
Journal title abbreviation:
Stem Cells Transl Med
Year:
2017
Journal volume:
6
Journal issue:
2
Pages contribution:
576-588
Language:
eng
Fulltext / DOI:
doi:10.5966/sctm.2015-0228
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28191758
Print-ISSN:
2157-6564
TUM Institution:
Neurologische Klinik und Poliklinik
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