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Title:

Impaired path integration in mice with disrupted grid cell firing.

Document type:
Journal Article
Author(s):
Gil, Mariana; Ancau, Mihai; Schlesiger, Magdalene I; Neitz, Angela; Allen, Kevin; De Marco, Rodrigo J; Monyer, Hannah
Abstract:
Path integration (PI) is a highly conserved, self-motion-based navigation strategy. Since the discovery of grid cells in the medial entorhinal cortex, neurophysiological data and computational models have suggested that these neurons serve PI. However, more direct empirical evidence supporting this hypothesis has been missing due to a lack of selective manipulations of grid cell activity and suitable behavioral assessments. Here we report that selective disruption of grid cell activity in mice c...     »
Journal title abbreviation:
Nat Neurosci
Year:
2018
Journal volume:
21
Journal issue:
1
Pages contribution:
81-91
Language:
eng
Fulltext / DOI:
doi:10.1038/s41593-017-0039-3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29230055
Print-ISSN:
1097-6256
TUM Institution:
Neurologische Klinik und Poliklinik
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