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Titel:

Tracking the Evolution of Cerebral Gadolinium-Enhancing Lesions to Persistent T1 Black Holes in Multiple Sclerosis: Validation of a Semiautomated Pipeline.

Dokumenttyp:
Journal Article
Autor(en):
Andermatt, Simon; Papadopoulou, Athina; Radue, Ernst-Wilhelm; Sprenger, Till; Cattin, Philippe
Abstract:
Some gadolinium-enhancing multiple sclerosis (MS) lesions remain T1-hypointense over months ("persistent black holes, BHs") and represent areas of pronounced tissue loss. A reduced conversion of enhancing lesions to persistent BHs could suggest a favorable effect of a medication on tissue repair. However, the individual tracking of enhancing lesions can be very time-consuming in large clinical trials.We created a semiautomated workflow for tracking the evolution of individual MS lesions, to calc...     »
Zeitschriftentitel:
J Neuroimaging
Jahr:
2017
Band / Volume:
27
Heft / Issue:
5
Seitenangaben Beitrag:
469-475
Sprache:
eng
Volltext / DOI:
doi:10.1111/jon.12439
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28370651
Print-ISSN:
1051-2284
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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