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Document type:
journal article 
Author(s):
Ziegler, Tilman; Hinkel, Rabea; Stöhr, Andrea; Eschenhagen, Thomas; Laugwitz, Karl-Ludwig; le Noble, Ferdinand; David, Robert; Hansen, Arne; Kupatt, Christian 
Title:
Thymosin 4 Improves Differentiation and Vascularization of EHTs. 
Abstract:
Induced pluripotent stem cells (iPSC) constitute a powerful tool to study cardiac physiology and represents a promising treatment strategy to tackle cardiac disease. However, iPSCs remain relatively immature after differentiation. Additionally, engineered heart tissue (EHT) has been investigated as a therapy option in preclinical disease models with promising results, although their vascularization and functionality leave room for improvement. Thymosin 4 (T4) has been shown to promote the differ...    »
 
Journal title abbreviation:
Stem Cells Int 
Year:
2017 
Journal volume:
2017 
Pages contribution:
6848271 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1687-966X 
TUM Institution:
Klinik und Poliklinik für Innere Medizin I