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Title:

Plasma Soluble Glycoprotein VI, Platelet Function, Bleeding, and Ischemic Events in Patients Undergoing Elective Percutaneous Coronary Intervention.

Document type:
Article; Journal Article
Author(s):
Lahu, Shqipdona; Adler, Kristin; Mayer, Katharina; Hein-Rothweiler, Ralph; Bernlochner, Isabell; Ndrepepa, Gjin; Schüpke, Stefanie; Holdenrieder, Stefan; Bongiovanni, Dario; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Gawaz, Meinrad; Massberg, Steffen; Kastrati, Adnan; Münch, Götz
Abstract:
BACKGROUND AND AIMS:  Glycoprotein VI (GPVI) is the major platelet-specific collagen receptor. GPVI shedding with generation of soluble GPVI (sGPVI) is an endogenous feedback mechanism preventing platelet overstimulation. sGPVI has not been investigated in patients with chronic coronary syndrome (CCS) undergoing percutaneous coronary intervention (PCI), especially regarding its potential value as a predictor of ischemic and bleeding risk. METHODS:  Baseline plasma sGPVI levels were available in...     »
Journal title abbreviation:
Thromb Haemost
Year:
2024
Journal volume:
124
Journal issue:
4
Pages contribution:
297-306
Fulltext / DOI:
doi:10.1055/s-0043-1772221
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37591289
Print-ISSN:
0340-6245
TUM Institution:
606; Klinik und Poliklinik für Innere Medizin I, Kardiologie (Prof. Laugwitz)
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