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Titel:

Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation.

Dokumenttyp:
Article; Journal Article
Autor(en):
Escher, Felicitas; Pietsch, Heiko; Aleshcheva, Ganna; Wenzel, Philip; Fruhwald, Friedrich; Stumpf, Christian; Westermann, Dirk; Bauersachs, Johann; Enseleit, Frank; Ruschitzka, Frank; Nägele, Herbert; Laugwitz, Karl-Ludwig; Haake, Hendrik; Frey, Norbert; Brachmann, Johannes; Huber, Kurt; Braun-Dullaeus, Rüdiger Christian; Bergmann, Martin W; Strotmann, Jörg; Grönefeld, Gerian; Krülls-Münch, Jürgen; Westenfeld, Ralf; Skurk, Carsten; Landmesser, Ulf; Pieske, Burkert; Gross, Ulrich M; Morawietz, La...     »
Abstract:
AIMS: The diagnostic approach to idiopathic giant-cell myocarditis (IGCM) is based on identifying various patterns of inflammatory cell infiltration and multinucleated giant cells (GCs) in histologic sections taken from endomyocardial biopsies (EMBs). The sampling error for detecting focally located GCs by histopathology is high, however. The aim of this study was to demonstrate the feasibility of gene profiling as a new diagnostic method in clinical practice, namely in a large cohort of patient...     »
Zeitschriftentitel:
J Clin Med
Jahr:
2020
Band / Volume:
9
Heft / Issue:
9
Volltext / DOI:
doi:10.3390/jcm9092689
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32825201
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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