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Title:

Sorting and magnetic-based isolation of reticulated platelets from peripheral blood.

Document type:
Article
Author(s):
Bernlochner, Isabell; Klug, Melissa; Larasati, Ditya; Von Scheidt, Moritz; Santovito, Donato; Hristov, Michael; Weber, Christian; Laugwitz, Karl-Ludwig; Bongiovanni, Dario
Abstract:
Reticulated Platelets (RPs) are large, RNA-rich, prothrombotic and hyperactive platelets known to be elevated in high-risk populations such as diabetics and patients with acute coronary syndrome. High levels of RPs correlate with mortality and adverse cardiovascular events in patients with coronary artery disease as well as with an insufficient antiplatelet response to thienopyridines and aspirin after percutaneous coronary interventions, making them an appealing drug target. However, processing...     »
Journal title abbreviation:
Platelets
Year:
2021
Journal volume:
32
Journal issue:
1
Pages contribution:
113-119
Fulltext / DOI:
doi:10.1080/09537104.2020.1724923
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32046562
Print-ISSN:
0953-7104
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert); Klinik und Poliklinik für Innere Medizin I, Kardiologie
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