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Titel:

Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation?

Dokumenttyp:
Journal Article
Autor(en):
Reichart, Bruno; Längin, Matthias; Radan, Julia; Mokelke, Maren; Buttgereit, Ines; Ying, Jiawei; Fresch, Ann Kathrin; Mayr, Tanja; Issl, Lara; Buchholz, Stefan; Michel, Sebastian; Ellgass, Reinhard; Mihalj, Maks; Egerer, Stefanie; Baehr, Andrea; Kessler, Barbara; Kemter, Elisabeth; Kurome, Mayuko; Zakhartchenko, Valeri; Steen, Stig; Sjöberg, Trygve; Paskevicius, Audrius; Krüger, Luise; Fiebig, Uwe; Denner, Joachim; Godehardt, Antonia W; Tönjes, Ralf R; Milusev, Anastasia; Rieben, Robert; Sfriso,...     »
Abstract:
BACKGROUND: The demand for donated human hearts far exceeds the number available. Xenotransplantation of genetically modified porcine organs provides an alternative. In 2000, an Advisory Board of the International Society for Heart and Lung Transplantation set the benchmark for commencing clinical cardiac xenotransplantation as consistent 60% survival of non-human primates after life-supporting porcine heart transplantations. Recently, we reported the stepwise optimization of pig-to-baboon ortho...     »
Zeitschriftentitel:
J Heart Lung Transplant
Jahr:
2020
Band / Volume:
39
Heft / Issue:
8
Seitenangaben Beitrag:
751-757
Volltext / DOI:
doi:10.1016/j.healun.2020.05.004
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32527674
Print-ISSN:
1053-2498
TUM Einrichtung:
1693; Klinik und Poliklinik für Innere Medizin I, Kardiologie
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