Benutzer: Gast  Login
Titel:

A decade of experience with genetically tailored pig models for diabetes and metabolic research.

Dokumenttyp:
Article; Proceedings Paper; Journal Article; Review
Autor(en):
Zettler, Silja; Renner, Simone; Kemter, Elisabeth; Hinrichs, Arne; Klymiuk, Nikolai; Backman, Mattias; Riedel, Evamaria Olga; Mueller, Christiane; Streckel, Elisabeth; Braun-Reichhart, Christina; Martins, Ana Sofia; Kurome, Mayuko; Keßler, Barbara; Zakhartchenko, Valeri; Flenkenthaler, Florian; Arnold, Georg Josef; Fröhlich, Thomas; Blum, Helmut; Blutke, Andreas; Wanke, Rüdiger; Wolf, Eckhard
Abstract:
The global prevalence of diabetes mellitus and other metabolic diseases is rapidly increasing. Animal models play pivotal roles in unravelling disease mechanisms and developing and testing therapeutic strategies. Rodents are the most widely used animal models but may have limitations in their resemblance to human disease mechanisms and phenotypes. Findings in rodent models are consequently often difficult to extrapolate to human clinical trials. To overcome this 'translational gap', we and other...     »
Zeitschriftentitel:
Anim Reprod
Jahr:
2020
Band / Volume:
17
Heft / Issue:
3
Volltext / DOI:
doi:10.1590/1984-3143-AR2020-0064
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33029223
Print-ISSN:
1806-9614
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
 BibTeX