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Titel:

Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial.

Dokumenttyp:
Journal Article
Autor(en):
Rau, Beate; Lang, Hauke; Koenigsrainer, Alfred; Gockel, Ines; Rau, Horst-Guenter; Seeliger, Hendrik; Lerchenmueller, Christian; Reim, Daniel; Wahba, Roger; Angele, Martin; Heeg, Steffen; Keck, Tobias; Weimann, Arved; Topp, Stefan; Piso, Pompiliu; Brandl, Andreas; Schuele, Silke; Jo, Peter; Pratschke, Johann; Wegel, Sandra; Rehders, Alexander; Moosmann, Nicolas; Gaedcke, Jochen; Heinemann, Volker; Trips, Evelyn; Loeffler, Markus; Schlag, Peter Michael; Thuss-Patience, Peter
Abstract:
PURPOSE: In patients with peritoneal metastasis (PM) from gastric cancer (GC), chemotherapy is the treatment of choice. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are still being debated. This randomized, controlled, open-label, multicenter phase III trial (EudraCT 2006-006088-22; ClinicalTrials.gov identifier: NCT02158988) explored the impact on overall survival (OS) of HIPEC after CRS. PATIENTS AND METHODS: Adult patients with GC and histologically prove...     »
Zeitschriftentitel:
J Clin Oncol
Jahr:
2024
Band / Volume:
42
Heft / Issue:
2
Seitenangaben Beitrag:
146-156
Volltext / DOI:
doi:10.1200/JCO.22.02867
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37906724
Print-ISSN:
0732-183X
TUM Einrichtung:
608; Klinik und Poliklinik für Chirurgie (Prof. Friess)
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