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Title:

Prediction of Tumor Cellularity in Resectable PDAC from Preoperative Computed Tomography Imaging.

Document type:
Journal Article
Author(s):
Jungmann, Friederike; Kaissis, Georgios A; Ziegelmayer, Sebastian; Harder, Felix; Schilling, Clara; Yen, Hsi-Yu; Steiger, Katja; Weichert, Wilko; Schirren, Rebekka; Demir, Ishan Ekin; Friess, Helmut; Makowski, Markus R; Braren, Rickmer F; Lohöfer, Fabian K
Abstract:
BACKGROUND: PDAC remains a tumor entity with poor prognosis and a 5-year survival rate below 10%. Recent research has revealed invasive biomarkers, such as distinct molecular subtypes, predictive for therapy response and patient survival. Non-invasive prediction of individual patient outcome however remains an unresolved task. METHODS: Discrete cellularity regions of PDAC resection specimen (n = 43) were analyzed by routine histopathological work up. Regional tumor cellularity and CT-derived Hou...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2021
Journal volume:
13
Journal issue:
9
Fulltext / DOI:
doi:10.3390/cancers13092069
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33922981
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Diagnostische und Interventionelle Radiologie; Klinik und Poliklinik für Chirurgie
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