The aim of the present study was to assess the improvement of image quality and diagnostic value of secretin-enhanced Magnetic Resonance Pancreatography compared with conventional MR pancreatography. 75 patients were examined with a T2-weighted single-shot-TSE-sequence (RARE). Image quality and diameter of the different parts of the pancreatic tract and diagnoses were assessed before and after intravenous administration of secretin. In patients with a normal pacreatic duct, the visualization was improved in all portions of the pancreatic tract. In patients with chronic pancreatitis and no ductal stricture a significant improvement in image quality after secretin injection was found, while in advanced disease with duct dilatation secretin stimulation provided no further diagnostic information. Secretin lead to an increase in diagnostic confidence for detection of pancreas divisum. In 13% of patients the diagnosis had to be corrected after secretin injection. In conclusion, secretin stimulation increases image quality and diagnosic value of MR pancreatography in patients with a normal or nondilated pancreatic duct.
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The aim of the present study was to assess the improvement of image quality and diagnostic value of secretin-enhanced Magnetic Resonance Pancreatography compared with conventional MR pancreatography. 75 patients were examined with a T2-weighted single-shot-TSE-sequence (RARE). Image quality and diameter of the different parts of the pancreatic tract and diagnoses were assessed before and after intravenous administration of secretin. In patients with a normal pacreatic duct, the visualization was...
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