In order to obtain objective data on skin disorders in subjects with atopic dermatitis (AE), we evaluated the skin of 70 children with AE and 31 healthy subjects, aged three months to eleven years by using non-invasive physical methodes. We studied the means of measurements of pH, capacitance and transepidermal water loss (TEWL) at five different skin locations. The eczematous skin leasions were graded by a lokal SCORAD. In general children with AE showed significant increased TEWL in particular, in children with positive familiy history of atopy. According to the phase of desease of eczematous skin TEWL and pH values were significantly higher whereas, capacitance values were significantly lower. Furthermore, by stdying means of measurements of pH we found a sex-linked difference: skin surface pH of females was not as acidic as those of males. As well, we obtained a negative correlation between age and skin surface hydration.
«
In order to obtain objective data on skin disorders in subjects with atopic dermatitis (AE), we evaluated the skin of 70 children with AE and 31 healthy subjects, aged three months to eleven years by using non-invasive physical methodes. We studied the means of measurements of pH, capacitance and transepidermal water loss (TEWL) at five different skin locations. The eczematous skin leasions were graded by a lokal SCORAD. In general children with AE showed significant increased TEWL in particular...
»