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Liver damage and immune responses.
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2025
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Chu, Talyn;Wu, Ming;Hoellbacher, Barbara;de Almeida, Gustavo P;Wurmser, Christine;Berner, Jacqueline;Donhauser, Lara V;Gerullis, Ann-Katrin;Lin, Siran;Cepeda-Mayorga, J Diego;Kilb, Iman I;Bongers, Lukas;Toppeta, Fabio;Strobl, Philipp;Youngblood, Ben;Schulz, Anna M;Zippelius, Alfred;Knolle, Percy A;Heinig, Matthias;Hackstein, Carl-Philipp;Zehn, Dietmar
Precursors of exhausted T cells are pre-emptively formed in acute infection.
Nature
2025
640
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Seitz, Stefanie;Dreyer, Tobias F;Stange, Christoph;Steiger, Katja;Wohlleber, Dirk;Anton, Martina;Pham, Thuý An;Sauter-Peschke, Dominique;Reuning, Ute;Multhoff, Gabriele;Weichert, Wilko;Kiechle, Marion;Magdolen, Viktor;Bronger, Holger
The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer.
Neoplasia
2025
60

Eckert, Stephan;Berner, Nicola;Kramer, Karl;Schneider, Annika;Müller, Julian;Lechner, Severin;Brajkovic, Sarah;Sakhteman, Amirhossein;Graetz, Christian;Fackler, Jonas;Dudek, Michael;Pfaffl, Michael W;Knolle, Percy;Wilhelm, Stephanie;Kuster, Bernhard
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics.
Nat Biotechnol
2025
43
3
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Elewaut, Anais;Estivill, Guillem;Bayerl, Felix;Castillon, Leticia;Novatchkova, Maria;Pottendorfer, Elisabeth;Hoffmann-Haas, Lisa;Schönlein, Martin;Nguyen, Trung Viet;Lauss, Martin;Andreatta, Francesco;Vulin, Milica;Krecioch, Izabela;Bayerl, Jonas;Pedde, Anna-Marie;Fabre, Naomi;Holstein, Felix;Cronin, Shona M;Rieser, Sarah;Laniti, Denarda Dangaj;Barras, David;Coukos, George;Quek, Camelia;Bai, Xinyu;Muñoz I Ordoño, Miquel;Wiesner, Thomas;Zuber, Johannes;Jönsson, Göran;Böttcher, Jan P;Vanharanta, Sakari;Obenauf, Anna C
Cancer cells impair monocyte-mediated T cell stimulation to evade immunity.
Nature
2025
637
8046
716-725