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- Title:
Combined proteomics and CRISPR Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Bahrami, Ehsan ; Schmid, Jan Philipp ; Jurinovic, Vindi ; Becker, Martin ; Wirth, Anna-Katharina ; Ludwig, Romina ; Kreissig, Sophie ; Duque Angel, Tania Vanessa ; Amend, Diana ; Hunt, Katharina ; Öllinger, Rupert ; Rad, Roland ; Frenz, Joris Maximilian ; Solovey, Maria ; Ziemann, Frank ; Mann, Matthias ; Vick, Binje ; Wichmann, Christian ; Herold, Tobias ; Jayavelu, Ashok Kumar ; Jeremias, Irmela
- Keywords:
- Research ; Genome Editing and the Future of Personalized and Targeted Cancer Medicine ; CRISPR-Cas9 in vivo screen ; Proteomics ; ADAM10 ; PDX ; Acute leukemia ; Leukemia stem cells ; Medical and Health Sciences
- Journal title:
- Molecular Cancer
- Year:
- 2023
- Journal volume:
- 22
- Journal issue:
- 1
- Fulltext / DOI:
- doi:10.1186/s12943-023-01803-0
- Publisher:
- BioMed Central
- E-ISSN:
- 1476-4598
- Date of publication:
- 08.07.2023
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