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Title:

Measuring cognitive impairment and monitoring cognitive decline in Huntington's disease: a comparison of assessment instruments.

Document type:
Journal Article
Author(s):
Horta-Barba, Andrea; Martinez-Horta, Saul; Pérez-Pérez, Jesús; Puig-Davi, Arnau; de Lucia, Natascia; de Michele, Giuseppe; Salvatore, Elena; Kehrer, Stefanie; Priller, Josef; Migliore, Simone; Squitieri, Ferdinando; Castaldo, Anna; Mariotti, Caterina; Mañanes, Veronica; Lopez-Sendon, Jose Luis; Rodriguez, Noelia; Martinez-Descals, Asunción; Júlio, Filipa; Januário, Cristina; Delussi, Marianna; de Tommaso, Marina; Noguera, Sandra; Ruiz-Idiago, Jesús; Sitek, Emilia J; Wallner, Renata; Nuzzi, Angel...     »
Abstract:
BACKGROUND: Progressive cognitive decline is an inevitable feature of Huntington's disease (HD) but specific criteria and instruments are still insufficiently developed to reliably classify patients into categories of cognitive severity and to monitor the progression of cognitive impairment. METHODS: We collected data from a cohort of 180 positive gene-carriers: 33 with premanifest HD and 147 with manifest HD. Using a specifically developed gold-standard for cognitive status we classified partic...     »
Journal title abbreviation:
J Neurol
Year:
2023
Journal volume:
270
Journal issue:
11
Pages contribution:
5408-5417
Fulltext / DOI:
doi:10.1007/s00415-023-11804-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37462754
Print-ISSN:
0340-5354
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie (Prof. Priller)
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