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- Titel:
What do patients' efficacy and tolerability ratings of acute migraine medication tell us? Cross-sectional data from the DMKG Headache Registry.
- Dokumenttyp:
- Article; Journal Article
- Autor(en):
- Ruscheweyh, Ruth; Dresler, Thomas; Förderreuther, Stefanie; Gaul, Charly; Gossrau, Gudrun; Jürgens, Tim Patrick; Ruschil, Victoria; Straube, Andreas; Scheidt, Jörg
- Abstract:
- BACKGROUND: Most migraine patients need an effective acute medication. Real-world data can provide important information on the performance of acute migraine medication in clinical practice. METHODS: We used data from the German Migraine and Headache Society Headache Registry, where patients rate efficacy and tolerability of and satisfaction with each of their acute headache medications. RESULTS: A total of 1756 adult migraine patients (females: 85%, age: 39.5 ± 12.8 years, headache days per month: 13.5 ± 8.1) were included. Of these, 93% used acute medication, most frequently triptans (59.3%) and/or non-opioid analgesics (56.4%), and 58.5% rated efficacy as good or very good. This was more frequent for triptans (75.4%) than for non-opioid analgesics (43.6%, p < 0.001). Among non-opioid analgesics, naproxen was rated most effective (61.9% very good or good, p < 0.001 compared to ibuprofen, acetylsalicylic acid and paracetamol). Patient-rated efficacy significantly declined with higher headache frequencies (p < 0.001), and this effect remained significant after omitting patients overusing acute medication. CONCLUSION: In the present population recruited at specialized headache centers, patients rated triptans as more effective than non-opioid analgesics, naproxen as more effective than ibuprofen, and acute medication efficacy decreased with increasing headache frequency.Trial registration: The German Migraine and Headache Society Headache Registry is registered with the German Clinical Trials Register (DRKS 00021081).
- Zeitschriftentitel:
- Cephalalgia
- Jahr:
- 2023
- Band / Volume:
- 43
- Heft / Issue:
- 5
- Volltext / DOI:
- doi:10.1177/03331024231174855
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/37177799
- Print-ISSN:
- 0333-1024
- TUM Einrichtung:
- 617; Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie (Prof. Henningsen)
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