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Title:

Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial.

Document type:
Journal Article
Author(s):
Rau, Beate; Lang, Hauke; Koenigsrainer, Alfred; Gockel, Ines; Rau, Horst-Guenter; Seeliger, Hendrik; Lerchenmueller, Christian; Reim, Daniel; Wahba, Roger; Angele, Martin; Heeg, Steffen; Keck, Tobias; Weimann, Arved; Topp, Stefan; Piso, Pompiliu; Brandl, Andreas; Schuele, Silke; Jo, Peter; Pratschke, Johann; Wegel, Sandra; Rehders, Alexander; Moosmann, Nicolas; Gaedcke, Jochen; Heinemann, Volker; Trips, Evelyn; Loeffler, Markus; Schlag, Peter Michael; Thuss-Patience, Peter
Abstract:
PURPOSE: In patients with peritoneal metastasis (PM) from gastric cancer (GC), chemotherapy is the treatment of choice. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are still being debated. This randomized, controlled, open-label, multicenter phase III trial (EudraCT 2006-006088-22; ClinicalTrials.gov identifier: NCT02158988) explored the impact on overall survival (OS) of HIPEC after CRS. PATIENTS AND METHODS: Adult patients with GC and histologically prove...     »
Journal title abbreviation:
J Clin Oncol
Year:
2024
Journal volume:
42
Journal issue:
2
Pages contribution:
146-156
Fulltext / DOI:
doi:10.1200/JCO.22.02867
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37906724
Print-ISSN:
0732-183X
TUM Institution:
608; Klinik und Poliklinik für Chirurgie (Prof. Friess)
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