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Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
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Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Nat Immunol
2023
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Bauer, Isabel J;Fang, Ping;Lämmle, Katrin F;Tyystjärvi, Sofia;Alterauge, Dominik;Baumjohann, Dirk;Yoon, Hongsup;Korn, Thomas;Wekerle, Hartmut;Kawakami, Naoto
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging.
Proc Natl Acad Sci U S A
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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nat Commun
2023
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Bertram, Dominic;Tsaktanis, Thanos;Berthele, Achim;Korn, Thomas
The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes.
Sci Rep
2023
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Wauschkuhn, Josephine;Solorza Buenrostro, Gilberto;Aly, Lilian;Asseyer, Susanna;Wicklein, Rebecca;Hartberger, Julia Maria;Ruprecht, Klemens;Mühlau, Mark;Schmitz-Hübsch, Tanja;Chien, Claudia;Berthele, Achim;Brandt, Alexander U;Korn, Thomas;Paul, Friedemann;Hemmer, Bernhard;Zimmermann, Hanna G;Knier, Benjamin
Retinal ganglion cell loss is associated with future disability worsening in early relapsing-remitting multiple sclerosis.
Eur J Neurol
2023
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Strong quenching of dye fluorescence in monomeric perylene orange/TMDC hybrid structures.
Nanoscale Adv.
2023
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Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation.
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Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis.
Front Immunol
2023
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