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Title:

Dosiomics and radiomics-based prediction of pneumonitis after radiotherapy and immune checkpoint inhibition: The relevance of fractionation.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Kraus, Kim Melanie; Oreshko, Maksym; Schnabel, Julia Anne; Bernhardt, Denise; Combs, Stephanie Elisabeth; Peeken, Jan Caspar
Abstract:
OBJECTIVES: Post-therapy pneumonitis (PTP) is a relevant side effect of thoracic radiotherapy and immunotherapy with checkpoint inhibitors (ICI). The influence of the combination of both, including dose fractionation schemes on PTP development is still unclear. This study aims to improve the PTP risk estimation after radio(chemo)therapy (R(C)T) for lung cancer with and without ICI by investigation of the impact of dose fractionation on machine learning (ML)-based prediction. MATERIALS AND METHOD...     »
Journal title abbreviation:
Lung Cancer
Year:
2024
Journal volume:
189
Fulltext / DOI:
doi:10.1016/j.lungcan.2024.107507
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38394745
Print-ISSN:
0169-5002
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie (Prof. Combs)
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