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Title:

The Transcription Factor HOXA5: Novel Insights into Metabolic Diseases and Adipose Tissue Dysfunction.

Document type:
Journal Article; Review; Research Support, Non-U.S. Gov't
Author(s):
Parrillo, Luca; Spinelli, Rosa; Longo, Michele; Zatterale, Federica; Santamaria, Gianluca; Leone, Alessia; Campitelli, Michele; Raciti, Gregory Alexander; Beguinot, Francesco
Abstract:
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its critical role in physiological activities in normal cells, such as organ development and body patterning, and pathological activities in cancer cells. Nonetheless, recent evidence supports the hypothesis of a role for HOXA5 in metabolic diseases, particularly in obesity and type 2 diabetes (T2D). In line with the current opinion that adipocyte and adipose tissue (AT) dysfunction belong to the group of prim...     »
Journal title abbreviation:
Cells
Year:
2023
Journal volume:
12
Journal issue:
16
Fulltext / DOI:
doi:10.3390/cells12162090
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37626900
TUM Institution:
Professur für Regenerative Medizin bei Kardiovaskulären Erkrankungen (Prof. Moretti)
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