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Titel:

Recapitulating porcine cardiac development in vitro: from expanded potential stem cell to embryo culture models.

Dokumenttyp:
Journal Article
Autor(en):
Rawat, Hilansi; Kornherr, Jessica; Zawada, Dorota; Bakhshiyeva, Sara; Kupatt, Christian; Laugwitz, Karl-Ludwig; Bähr, Andrea; Dorn, Tatjana; Moretti, Alessandra; Nowak-Imialek, Monika
Abstract:
Domestic pigs (Sus scrofa) share many genetic, anatomical, and physiological traits with humans and therefore constitute an excellent preclinical animal model. Fundamental understanding of the cellular and molecular processes governing early porcine cardiogenesis is critical for developing advanced porcine models used for the study of heart diseases and new regenerative therapies. Here, we provide a detailed characterization of porcine cardiogenesis based on fetal porcine hearts at various devel...     »
Zeitschriftentitel:
Front Cell Dev Biol
Jahr:
2023
Band / Volume:
11
Volltext / DOI:
doi:10.3389/fcell.2023.1111684
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37261075
TUM Einrichtung:
Klinik und Poliklinik für Innere Medizin I, Kardiologie; Professur für Regenerative Medizin bei Kardiovaskulären Erkrankungen (Prof. Moretti)
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