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Dokumenttyp:
Article; Review; Journal Article
Autor(en):
Kupatt, Christian; Ziegler, Tilman; Bähr, Andrea; Le Noble, Ferdinand
Titel:
Thymosin ß4 and MRTF-A mitigate vessel regression despite cardiovascular risk factors.
Abstract:
Since clinical revascularization techniques of coronary or peripheral artery disease (CAD/PAD) focus on macrovessels of the heart, the microcirculatory compartment largely goes unnoticed. However, cardiovascular risk factors not only drive large vessel atherosclerosis, but also microcirculatory rarefaction, an instance unmet by current therapeutic schemes. Angiogenic gene therapy has the potential to reverse capillary rarefaction, but only if the disease-causing inflammation and vessel-destabili...     »
Zeitschriftentitel:
Int Immunopharmacol
Jahr:
2023
Band / Volume:
117
Volltext / DOI:
doi:10.1016/j.intimp.2023.109786
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36812671
Print-ISSN:
1567-5769
TUM Einrichtung:
Klinik und Poliklinik für Innere Medizin I, Kardiologie
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