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Su, Jinpeng;Brunner, Livia;Ates Oz, Edanur;Sacherl, Julia;Frank, Geraldine;Kerth, Helene Anne;Thiele, Frank;Wiegand, Marian;Mogler, Carolin;Aguilar, Julio Cesar;Knolle, Percy A;Collin, Nicolas;Kosinska, Anna D;Protzer, Ulrike
Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models.
J Hepatol
2023
78
4
717-730

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Yahoo, Neda;Dudek, Michael;Knolle, Percy;Heikenwälder, Mathias
Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation.
J Hepatol
2023
79
2
538-551

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Bergant, Valter;Schnepf, Daniel;de Andrade Krätzig, Niklas;Hubel, Philipp;Urban, Christian;Engleitner, Thomas;Dijkman, Ronald;Ryffel, Bernhard;Steiger, Katja;Knolle, Percy A;Kochs, Georg;Rad, Roland;Staeheli, Peter;Pichlmair, Andreas
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Nat Commun
2023
14
1

Mehr ...

Hackstein, Carl-Philipp;Spitzer, Jasper;Symeonidis, Konstantinos;Horvatic, Helena;Bedke, Tanja;Steglich, Babett;Klein, Sabine;Assmus, Lisa M;Odainic, Alexandru;Szlapa, Jennifer;Kessler, Nina;Beyer, Marc;Schmithausen, Ricarda;Latz, Eicke;Flavell, Richard A;Garbi, Natalio;Kurts, Christian;Kümmerer, Beate M;Trebicka, Jonel;Roers, Axel;Huber, Samuel;Schmidt, Susanne V;Knolle, Percy A;Abdullah, Zeinab
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
J Hepatol
2023
79
1
150-166

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Esser, Knud;Cheng, Xiaoming;Wettengel, Jochen M;Lucifora, Julie;Hansen-Palmus, Lea;Austen, Katharina;Roca Suarez, Armando A;Heintz, Sarah;Testoni, Barbara;Nebioglu, Firat;Pham, Minh Tu;Yang, Shangqing;Zernecke, Alma;Wohlleber, Dirk;Ringelhan, Marc;Broxtermann, Mathias;Hartmann, Daniel;Hüser, Norbert;Mergner, Julia;Pichlmair, Andreas;Thasler, Wolfgang E;Heikenwalder, Mathias;Gasteiger, Georg;Blutke, Andreas;Walch, Axel;Knolle, Percy A;Bartenschlager, Ralf;Protzer, Ulrike
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes.
Cell Mol Gastroenterol Hepatol
2023
16
2
201-221

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Wang, Xiaobo;Istvanffy, Rouzanna;Ye, Linhan;Teller, Steffen;Laschinger, Melanie;Diakopoulos, Kalliope N;Görgülü, Kıvanç;Li, Qiaolin;Ren, Lei;Jäger, Carsten;Steiger, Katja;Muckenhuber, Alexander;Vilne, Baiba;Çifcibaşı, Kaan;Mota Reyes, Carmen;Yurteri, Ümmügülsüm;Kießler, Maximilian;Gürçınar, Ibrahim H;Sugden, Maya M;Yıldızhan, Saliha Elif;Sezerman, Osman Ugur;Çilingir, Sümeyye;Süyen, Güldal;Reichert, Maximilian;Schmid, Roland M;Bärthel, Stefanie;Öllinger, Rupert;Krüger, Achim;Rad, Roland;Saur, Dieter;Algül, Hana;Friess, Helmut;Lesina, Marina;Ceyhan, Güralp Onur;Demir, Ihsan Ekin
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
J Clin Invest
2023
133
21

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Kotsiliti, Elena;Leone, Valentina;Schuehle, Svenja;Govaere, Olivier;Li, Hai;Wolf, Monika J;Horvatic, Helena;Bierwirth, Sandra;Hundertmark, Jana;Inverso, Donato;Zizmare, Laimdota;Sarusi-Portuguez, Avital;Gupta, Revant;O'Connor, Tracy;Giannou, Anastasios D;Shiri, Ahmad Mustafa;Schlesinger, Yehuda;Beccaria, Maria Garcia;Rennert, Charlotte;Pfister, Dominik;Öllinger, Rupert;Gadjalova, Iana;Ramadori, Pierluigi;Rahbari, Mohammad;Rahbari, Nuh;Healy, Marc;Fernández-Vaquero, Mirian;Yahoo, Neda;Janzen, Jakob;Singh, Indrabahadur;Fan, Chaofan;Liu, Xinyuan;Rau, Monika;Feuchtenberger, Martin;Schwaneck, Eva;Wallace, Sebastian J;Cockell, Simon;Wilson-Kanamori, John;Ramachandran, Prakash;Kho, Celia;Kendall, Timothy J;Leblond, Anne-Laure;Keppler, Selina J;Bielecki, Piotr;Steiger, Katja;Hofmann, Maike;Rippe, Karsten;Zitzlesberger, Horst;Weber, Achim;Malek, Nisar;Lüdde, Tom;Vucur, Mihael;Augustin, Hellmut G;Flavell, Richard;Parnas, Oren;Rad, Roland;Pabst, Olivier;Henderson, Neil C;Huber, Samuel;Macpherson, Andrew;Knolle, Percy;Claasen, Manfred;Geier, Andreas;Trautwein, Christoph;Unger, Kristian;Elinav, Eran;Waisman, Ari;Abdullah, Zeinab;Haller, Dirk;Tacke, Frank;Anstee, Quentin M;Heikenwalder, Mathias
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
J Hepatol
2023
79
2
296-313

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Bayerl, Felix;Meiser, Philippa;Donakonda, Sainitin;Hirschberger, Anna;Lacher, Sebastian B;Pedde, Anna-Marie;Hermann, Chris D;Elewaut, Anais;Knolle, Moritz;Ramsauer, Lukas;Rudolph, Thomas J;Grassmann, Simon;Öllinger, Rupert;Kirchhammer, Nicole;Trefny, Marcel;Anton, Martina;Wohlleber, Dirk;Höchst, Bastian;Zaremba, Anne;Krüger, Achim;Rad, Roland;Obenauf, Anna C;Schadendorf, Dirk;Zippelius, Alfred;Buchholz, Veit R;Schraml, Barbara U;Böttcher, Jan P
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity
2023
56
6
1341-1358.e11

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Keppler-Hafkemeyer, Andrea;Greil, Christine;Wratil, Paul R;Shoumariyeh, Khalid;Stern, Marcel;Hafkemeyer, Annika;Ashok, Driti;Hollaus, Alexandra;Lupoli, Gaia;Priller, Alina;Bischof, Marie L;Ihorst, Gabriele;Engelhardt, Monika;Marks, Reinhard;Finke, Jürgen;Bertrand, Hannah;Dächert, Christopher;Muenchhoff, Maximilian;Badell, Irina;Emmerich, Florian;Halder, Hridi;Spaeth, Patricia M;Knolle, Percy A;Protzer, Ulrike;von Bergwelt-Baildon, Michael;Duyster, Justus;Hartmann, Tanja N;Moosmann, Andreas;Keppler, Oliver T
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Nat. Cancer
2023
4
1
81-95

Mehr ...

Klüpfel, Julia;Paßreiter, Sandra;Rumpf, Melina;Christa, Catharina;Holthoff, Hans-Peter;Ungerer, Martin;Lohse, Martin;Knolle, Percy;Protzer, Ulrike;Elsner, Martin;Seidel, Michael
Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay.
Anal Bioanal Chem
2023
415
3
391-404