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Titel:

Return of individual genomic research results within the PRAEGNANT multicenter registry study.

Dokumenttyp:
Article; Journal Article
Autor(en):
Huebner, Hanna; Ruebner, Matthias; Kurbacher, Christian; Hadji, Peyman; Hartkopf, Andreas D; Lux, Michael P; Huober, Jens; Uhrig, Sabrina; Taran, Florin-Andrei; Overkamp, Friedrich; Tesch, Hans; Häberle, Lothar; Lüftner, Diana; Wallwiener, Markus; Müller, Volkmar; Beckmann, Matthias W; Hein, Alexander; Belleville, Erik; Untch, Michael; Janni, Wolfgang; Fehm, Tanja N; Kolberg, Hans-Christian; Wallwiener, Diethelm; Brucker, Sara Y; Schneeweiss, Andreas; Ettl, Johannes; Fasching, Peter A; Michel, L...     »
Abstract:
PURPOSE: The PRAEGNANT study is a registry study for metastatic breast cancer patients, focusing on biomarker detection. Recently, within this study, genetic alterations in 37 breast cancer predisposition genes were analyzed and genetic findings were detected for 396 participants. The aim of this project was to return genetic results to the physicians and to analyze actions taken (e.g., disclosure of results to patients, validation of results, clinical impact, and impact on the patient's quality...     »
Zeitschriftentitel:
Breast Cancer Res Treat
Jahr:
2023
Band / Volume:
197
Heft / Issue:
2
Seitenangaben Beitrag:
355-368
Volltext / DOI:
doi:10.1007/s10549-022-06795-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36409394
Print-ISSN:
0167-6806
TUM Einrichtung:
145; 45; Klinik und Poliklinik für Frauenheilkunde
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