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Title:

Genomic, biochemical and expressional properties reveal strong conservation of the CLCA2 gene in birds and mammals.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bartenschlager, Florian; Klymiuk, Nikolai; Gruber, Achim D; Mundhenk, Lars
Abstract:
Recent studies have revealed the dynamic and complex evolution of CLCA1 gene homologues in and between mammals and birds with a particularly high diversity in mammals. In contrast, CLCA2 has only been found as a single copy gene in mammals, to date. Furthermore, CLCA2 has only been investigated in few mammalian species but not in birds. Here, we established core genomic, protein biochemical and expressional properties of CLCA2 in several bird species and compared them with mammalian CLCA2. Chick...     »
Journal title abbreviation:
PeerJ
Year:
2022
Journal volume:
10
Fulltext / DOI:
doi:10.7717/peerj.14202
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36389428
TUM Institution:
Professur für Kardiovaskuläre Translation in Großtiermodellen (Prof. Klymiuk)
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