User: Guest  Login
Title:

Evolutionarily conserved properties of CLCA proteins 1, 3 and 4, as revealed by phylogenetic and biochemical studies in avian homologues.

Document type:
Article; Journal Article
Author(s):
Bartenschlager, Florian; Klymiuk, Nikolai; Weise, Christoph; Kuropka, Benno; Gruber, Achim D; Mundhenk, Lars
Abstract:
Species-specific diversities are particular features of mammalian chloride channel regulator, calcium activated (CLCA) genes. In contrast to four complex gene clusters in mammals, only two CLCA genes appear to exist in chickens. CLCA2 is conserved in both, while only the galline CLCA1 (gCLCA1) displays close genetic distance to mammalian clusters 1, 3 and 4. In this study, sequence analyses and biochemical characterizations revealed that gCLCA1 as a putative avian prototype shares common protein...     »
Journal title abbreviation:
PLoS ONE
Year:
2022
Journal volume:
17
Journal issue:
4
Fulltext / DOI:
doi:10.1371/journal.pone.0266937
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35417490
Print-ISSN:
1932-6203
TUM Institution:
Professur für Kardiovaskuläre Translation in Großtiermodellen (Prof. Klymiuk)
 BibTeX