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Titel:

Hypoxia Preconditioned Serum (HPS) Promotes Proliferation and Chondrogenic Phenotype of Chondrocytes In Vitro.

Dokumenttyp:
Journal Article
Autor(en):
Jiang, Jun; Altammar, Jannat; Cong, Xiaobin; Ramsauer, Lukas; Steinbacher, Vincent; Dornseifer, Ulf; Schilling, Arndt F; Machens, Hans-Günther; Moog, Philipp
Abstract:
Autologous chondrocyte implantation (ACI) for the treatment of articular cartilage defects remains challenging in terms of maintaining chondrogenic phenotype during in vitro chondrocyte expansion. Growth factor supplementation has been found supportive in improving ACI outcomes by promoting chondrocyte redifferentiation. Here, we analysed the chondrogenic growth factor concentrations in the human blood-derived secretome of Hypoxia Preconditioned Serum (HPS) and assessed the effect of HPS-10% and...     »
Zeitschriftentitel:
Int J Mol Sci
Jahr:
2023
Band / Volume:
24
Heft / Issue:
13
Volltext / DOI:
doi:10.3390/ijms241310441
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37445617
Print-ISSN:
1422-0067
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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