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Titel:

Promising novel therapeutic targets for kidney disease: Emphasis on kidney-specific proteins.

Dokumenttyp:
Journal Article; Review
Autor(en):
Tejeswini Sen, Tathambika; Kale, Ajinath; Lech, Maciej; Anders, Hans-Joachim; Gaikwad, Anil Bhanudas
Abstract:
Worldwide, around 850 million people are diagnosed with kidney disease but the available treatment options are still limited. Preclinical studies propose a plethora of druggable targets that can attenuate kidney disease and could qualify as novel therapeutic strategies, although most of these targets still await clinical testing. Here, we review some promising candidate targets for chronic kidney disease: intermedin, periostin, sirtuin, the cannabinoid receptor, Klotho, and uromodulin. For acute...     »
Zeitschriftentitel:
Drug Discov Today
Jahr:
2023
Band / Volume:
28
Heft / Issue:
2
Volltext / DOI:
doi:10.1016/j.drudis.2022.103466
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36509391
Print-ISSN:
1359-6446
TUM Einrichtung:
Professur für Nephrologie (Prof. Heemann)
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