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Title:

Pharmacokinetics of metamizole (dipyrone) as an add-on in calves undergoing umbilical surgery.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Fux, Daniela; Metzner, Moritz; Brandl, Johanna; Feist, Melanie; Behrendt-Wippermann, Magdalena; von Thaden, Anne; Baumgartner, Christine
Abstract:
This preliminary clinical investigation of the pharmacokinetic behavior of the main metamizole (dipyrone) metabolites 4-methylaminoantipyrine (4-MAA) and 4-aminoantipyrine (4-AA) in calves undergoing umbilical surgery is part of an already published main study. A single intravenous dose of metamizole was added to ketamine/xylazine/isoflurane anesthesia. Eight Simmental calves weighing 90 ± 10.8 kg and aged 47.6 ± 10.4 days received 40 mg/kg metamizole intravenously 10 minutes prior to general an...     »
Journal title abbreviation:
PLoS ONE
Year:
2022
Journal volume:
17
Journal issue:
3
Fulltext / DOI:
doi:10.1371/journal.pone.0265305
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35290991
Print-ISSN:
1932-6203
TUM Institution:
Departments
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