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Title:

PET-directed combined modality therapy for gastroesophageal junction cancer: Results of the multicentre prospective MEMORI trial of the German Cancer Consortium (DKTK).

Document type:
Article; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Author(s):
Lorenzen, Sylvie; Quante, Michael; Rauscher, Isabel; Slotta-Huspenina, Julia; Weichert, Wilko; Feith, Marcus; Friess, Helmut; Combs, Stefanie E; Weber, Wolfgang A; Haller, Bernhard; Angele, Martin; Albertsmeier, Markus; Blankenstein, Christiane; Kasper, Stefan; Schmid, Roland M; Bassermann, Florian; Schwaiger, Markus; Liffers, Sven-Thorsten; Siveke, Jens T
Abstract:
BACKGROUND: Positron emission tomography (PET) may differentiate responding and non-responding tumours early in the treatment of locally advanced gastroesophageal junction adenocarcinomas. Early PET non-responders (P-NR) after induction CTX might benefit from changing to chemoradiation (CRT). METHODS: Patients underwent baseline 18F-FDG PET followed by 1 cycle of CTX. PET was repeated at day 14-21 and responders (P-R), defined as ≥35% decrease in SUVmean from baseline, continued with CTX. P-NR s...     »
Journal title abbreviation:
Eur J Cancer
Year:
2022
Journal volume:
175
Pages contribution:
99-106
Fulltext / DOI:
doi:10.1016/j.ejca.2022.07.027
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36099671
Print-ISSN:
0959-8049
TUM Institution:
591; Departments; Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Institut für KI und Informatik in der Medizin (Prof. Rückert); Klinik und Poliklinik für Chirurgie (Prof. Friess); Klinik und Poliklinik für Innere Medizin II, Gastroenterologie (Prof. Schmid); Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie (Prof. Bassermann); Klinik und Poliklinik für Nuklearmedizin (Prof. Weber); Klinik und Poliklinik für RadioOnkologie und Strahlenthera...     »
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