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Title:

Hypoxia Preconditioned Serum (HPS)-Hydrogel Can Accelerate Dermal Wound Healing in Mice-An In Vivo Pilot Study.

Document type:
Journal Article
Author(s):
Jiang, Jun; Kraneburg, Ursula; Dornseifer, Ulf; Schilling, Arndt F; Hadjipanayi, Ektoras; Machens, Hans-Günther; Moog, Philipp
Abstract:
The ability to use the body's resources to promote wound repair is increasingly becoming an interesting area of regenerative medicine research. Here, we tested the effect of topical application of blood-derived hypoxia preconditioned serum (HPS) on wound healing in a murine wound model. Alginate hydrogels loaded with two different HPS concentrations (10 and 40%) were applied topically on full-thickness wounds created on the back of immunocompromised mice. We achieved a significant dose-dependent...     »
Journal title abbreviation:
Biomedicines
Year:
2022
Journal volume:
10
Journal issue:
1
Fulltext / DOI:
doi:10.3390/biomedicines10010176
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35052855
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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